Superior Vena Cava Syndrome SVCS – Caused by Obstruction Caused by direct obstruction of the superior vena cava Usually by malignancies of lung tumors, thymomas or mediastinal lymphadenopathies. Most common is Bronchiogenic carcinoma Signs and Symptoms of Superior Vena Cava Syndrome Facial Edema Venous distention in the neck Arm edema Cough Bluish tint, not to be confused with Tyndall effect from Hyaluronic Dermal Filler injections development of facial flushing, distended neck veins when raising arms above head.